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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
BLM
All Species:
17.58
Human Site:
T1223
Identified Species:
29.74
UniProt:
P54132
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P54132
NP_000048.1
1417
159000
T1223
K
K
C
L
G
E
L
T
E
V
C
K
S
L
G
Chimpanzee
Pan troglodytes
XP_510594
1417
158822
T1223
K
K
C
L
G
E
L
T
E
V
C
K
S
L
G
Rhesus Macaque
Macaca mulatta
XP_001097543
1416
158885
T1222
K
K
C
L
G
E
L
T
E
V
C
K
S
L
G
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
O88700
1416
158347
K1222
Q
R
E
E
V
V
K
K
C
L
G
E
L
T
E
Rat
Rattus norvegicus
Q6AYJ1
621
69624
M432
R
I
S
S
M
V
V
M
E
N
V
G
Q
Q
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001515695
791
89186
G602
K
A
L
G
K
V
F
G
V
H
Y
F
N
I
F
Chicken
Gallus gallus
Q9I920
1142
126164
T953
K
K
C
L
G
E
L
T
D
T
C
K
T
L
G
Frog
Xenopus laevis
Q9DEY9
1364
152305
T1175
K
K
C
Q
A
E
L
T
E
L
C
K
R
L
G
Zebra Danio
Brachydanio rerio
XP_701357
1261
139417
V1072
F
C
K
E
H
P
E
V
I
C
D
N
C
A
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VGI8
1487
166060
L1294
E
R
C
Y
T
D
L
L
D
L
C
R
T
I
A
Honey Bee
Apis mellifera
XP_396209
961
109321
Y772
R
R
T
Q
Q
L
N
Y
F
G
E
I
F
D
R
Nematode Worm
Caenorhab. elegans
O18017
988
110641
K799
V
S
E
A
Q
A
L
K
E
R
H
M
V
K
H
Sea Urchin
Strong. purpuratus
XP_001175892
1394
152920
K1198
V
D
V
T
E
E
A
K
S
L
V
R
F
V
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P35187
1447
163819
G1249
L
R
S
Y
T
Y
G
G
S
T
M
G
S
S
H
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
96.1
N.A.
N.A.
76.9
21.2
N.A.
46.3
47.9
50.8
41.6
N.A.
27.8
30.9
26.5
31.5
Protein Similarity:
100
99.2
97.7
N.A.
N.A.
85.2
30.9
N.A.
50.1
60.7
66.6
54
N.A.
47
47.1
40.2
47.6
P-Site Identity:
100
100
100
N.A.
N.A.
0
6.6
N.A.
6.6
80
73.3
0
N.A.
20
0
13.3
13.3
P-Site Similarity:
100
100
100
N.A.
N.A.
26.6
20
N.A.
20
93.3
80
0
N.A.
73.3
13.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
8
8
8
8
0
0
0
0
0
0
8
8
% A
% Cys:
0
8
43
0
0
0
0
0
8
8
43
0
8
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
15
0
8
0
0
8
0
% D
% Glu:
8
0
15
15
8
43
8
0
43
0
8
8
0
0
8
% E
% Phe:
8
0
0
0
0
0
8
0
8
0
0
8
15
0
8
% F
% Gly:
0
0
0
8
29
0
8
15
0
8
8
15
0
0
43
% G
% His:
0
0
0
0
8
0
0
0
0
8
8
0
0
0
15
% H
% Ile:
0
8
0
0
0
0
0
0
8
0
0
8
0
15
0
% I
% Lys:
43
36
8
0
8
0
8
22
0
0
0
36
0
8
8
% K
% Leu:
8
0
8
29
0
8
50
8
0
29
0
0
8
36
0
% L
% Met:
0
0
0
0
8
0
0
8
0
0
8
8
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
0
0
8
0
8
8
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
15
15
0
0
0
0
0
0
0
8
8
0
% Q
% Arg:
15
29
0
0
0
0
0
0
0
8
0
15
8
0
15
% R
% Ser:
0
8
15
8
0
0
0
0
15
0
0
0
29
8
0
% S
% Thr:
0
0
8
8
15
0
0
36
0
15
0
0
15
8
0
% T
% Val:
15
0
8
0
8
22
8
8
8
22
15
0
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
15
0
8
0
8
0
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _